Table 2. Cox analysis for disease-free survival in breast cancer cohort #1.
Parameters | Unadjusted | Adjusted* | ||
---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
TERT gain (yes vs no) | 3.8 (1.4-10.3) | 0.0078 | 3.0 (1.1-8.4) | 0.032 |
TERT T349C (yes vs no) | 2.8 (1.0-7.7) | 0.047 | 2.3 (0.9-6.6) | 0.096 |
MYC (high vs low)** | 3.5 (1.1-10.8) | 0.031 | 3.2 (1.1-10.1) | 0.045 |
Chevallier's classification (3-4 vs 1-2) | 3.6 (1.1-12.6) | 0.048 | - | - |
*Adjusted for treatment response according to Chevallier's classification: incomplete pathologic response, classes 3-4, vs complete pathologic response, classes 1-2.
**High > median, low < median (181)
Hazard ratio, HR; 95% confidence interval, 95% CI.