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. 2017 Sep 12;8(44):77846–77859. doi: 10.18632/oncotarget.20840

Figure 5. Frequency of NAPRT staining in human lung and brain cancers.

Figure 5

(A) A representative comparison of NAPRT expression levels in human tumor-adjacent normal brain tissue (upper left) and glioblastoma tumor tissue (upper right) or in normal lung (lower left) compared to small cell lung carcinoma (lower right). Each sample was stained with 3C6D2 and CAT hematoxylin. Scale bars: 100 μm (brain) and 40 μm (lung). (B) Lung or (C) brain cancer tumor micro arrays (TMAs) were stained with 3C6D2/CAT hematoxylin by IHC to determine expression levels of NAPRT protein. The frequency NAPRT positive cancerous cells within the tumor sample was scored as 0-10 % (white), 11-90 % (grey) or 91-100 % (black) positively stained. Samples scored as equivocal (hatched bars) could not be evaluated. The results are indicated as the percentage of total cases examined within a tumor sub-type. n = the number of different tumor cases evaluated.