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. 2017 Aug 16;8(44):77963–77974. doi: 10.18632/oncotarget.20276

Table 2. The association of polymorphisms in microRNA 30c-1 and microRNA 27a with overall survival.

SNP Genotypes Num MST Log-rank P value HR 95% CI (P value) aHR 95% CI (P value)
microRNA 30c-1 AA 133 28.44 0.054 1.00 1.00
rs928508 AG 229 23.20 1.28 1.01–1.61 (0.041) 1.30 1.03–1.65 (0.027)
GG 92 21.95 1.37 1.03–1.83 (0.033) 1.45 1.08–1.94 (0.012)
AG 229 23.20 0.592 1.00 1.00
GG 92 21.95 1.07 0.83–1.39 (0.593) 1.09 0.84–1.43 (0.514)
AA/AG 362 25.25 0.188 1.00 1.00
GG 92 21.95 1.18 0.92–1.51 (0.190) 1.24 0.96–1.59 (0.097)
AA 133 28.44 0.019 1.00 1.00
AG/GG 321 22.86 1.30 1.04–1.62 (0.020) 1.34 1.07–1.67 (0.010)
A allele 495 26.04 0.022 1.00 1.00
G allele 413 22.63 1.18 1.02–1.36 (0.023) 1.21 1.05–1.39 (0.009)
microRNA 27a TT 247 26.27 0.033 1.00 1.00
rs895819 CT 167 23.71 1.17 0.95–1.45 (0.143) 1.23 0.99–1.52 (0.062)
CC 40 18.25 1.56 1.09–2.22 (0.014) 1.71 1.20–2.45 (0.003)
CT 167 23.71 0.100 1.00 1.00
CC 40 18.25 1.35 0.94–1.95 (0.102) 1.44 1.00–2.08 (0.050)
CT/TT 414 25.23 0.030 1.00 1.00
CC 40 18.25 1.46 1.04–2.05 (0.031) 1.57 1.11–2.21 (0.010)
TT 247 26.27 0.041 1.00 1.00
CC/CT 207 22.79 1.23 1.01–1.50 (0.042) 1.30 1.06–1.50 (0.012)
T allele 661 25.62 0.011 1.00 1.00
C allele 247 22.14 1.22 1.05–1.43 (0.012) 1.28 1.09–1.49 (0.002)

*Num: the patients number for each genotype, aHR: adjusted HR for histological type, clinical stage and, receipt of chemotherapy and surgery.