Table 5. Pooled HR and 95% CIs of microRNA 27a rs895819.
Outcome | Model | No. of studies | No. of patients | HR (95% CI) | P-value | Heterogeneity (I2, P-value) |
---|---|---|---|---|---|---|
OS | CT vs TT | 6 | 3235 | 1.133 (0.923, 1.391) | 0.232 | 56.8%, 0.041 |
CC vs TT | 7 | 3909 | 1.296 (1.027, 1.636) | 0.029 | 54.3%, 0.041 | |
CC + CT vs TT | 5 | 3135 | 1.176 (0.916, 1.509) | 0.204 | 68.9%, 0.012 | |
CC vs CT + TT | 3 | 1953 | 1.220 (0.975, 1.526) | 0.082 | 9.8%, 0.330 | |
RFS | CT vs TT | 2 | 948 | 1.117 (0.892, 1.400) | 0.335 | 0.0%, 0.891 |
CC vs TT | 2 | 948 | 0.979 (0.762, 1.256) | 0.866 | 0.0%, 0.558 | |
CC + CT vs TT | 2 | 948 | 1.091 (0.899, 1.323) | 0.380 | 0.0%, 0.791 |
OS: overall survival, RFS: recurrence-free survival.