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. 2017 Aug 31;8(44):78208–78224. doi: 10.18632/oncotarget.20596

Table 6. Potentially suitable materials possible to use in the future construction of depot supporting tools for HIPEC and PIPAC.

Type of used material Type of experimental intervention Reference
Pegylated silica-core gold nanoshells (pSGNs) in vivo with external near-infrared (NIR) laser irradiation. Experimental nanoparticle-induced intraperitoneal hyperthermia and targeted photoablation in treating ovarian cancer. Wu et. al. [103]
Thermosensitive hydrogel system (PTX/PECT(gel)) assembled by PTX (paclitaxel)-loaded amphiphilic copolymer Thermosensitive hydrogel system used in experimental for sustained intraperitoneal chemotherapy of peritoneal carcinomatosis. Xu et. al. [21]
Nanovehicles based on anti-CD133 antibodies bioconiugated to carbon nanotubes loaded with platinum (Pt) –prodrugs Nanovehicles used as a novel target strategy for hyperthermic intraperitoneal chemotherapy on mouse melanoma B16 PC model. Nowacki et. al. [32]
Curcumin loaded polymeric micelles (Cur-M) Anti-Tumor Activity of Curcumin by Polymeric Micelles in Thermosensitive Hydrogel System tested in Colorectal Peritoneal Carcinomatosis Model Zhang et al. [131]
Paclitaxel-loaded pH-responsive expansile nanoparticles (Pax-eNP) Expansile nanoparticles used in in vitro and in vivo murine models of malignant peritoneal mesothelioma Colson et al. [142]
Paclitaxel loading nanoparticle (PLA) by ultrasonic emulsification Nanoparticles tested in vitro on rat ovarian carcinoma cells and in vivo on PC induced in F344 rats Lu et al. [132]
Combination of 5-fluorouracil (5-FU) loaded polymeric micelles and cisplatin (DDP) in biodegradable thermosensitive chitosan (CS) hydrogel Nanosystems tested on colorectal peritoneal carcinomatosis mouse model Yun et al. [133]