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Diversity analyses. (A) Rarefaction curves of alpha diversity indices. Left: chao1 (species richness); right, Faith’s phylogenetic diversity index. (B) Beta diversity shown by principal coordinates analysis (PCoA) of unweighted Unifrac distances (left) and weighted Unifrac distances (right). The plaque microbial communities significantly clustered by caries status (P < 0.05, analysis of similarity). S-ECC, severe early childhood caries.
