Table 2.
Relative Abundance of the Top 25 Species- and Genus-Level OTUs Detected in Plaque of Caries-Free Children and Children with S-ECC.
| Median Relative Abundance, % (Range) |
||
|---|---|---|
| OTU | Caries Free (n = 20) | S-ECC (n = 30) |
| Species level | ||
| Streptococcus HOT 058 | 23.7 (12.3 to 42.0) | 26.7 (11.1 to 42.3) |
| Leptotrichia shahii | 3.4 (0 to 16.7) | 2.1 (0.2 to 11.7) |
| Lautropia mirabilis | 3.2 (0.2 to 11.6) | 2.2 (0.05 to 10.0) |
| Haemophilus parainfluenzae | 2.0 (0.01 to 7.2) | 3.1 (0.12 to 12.6) |
| Veillonella dispar | 2.2 (0.15 to 9.4) | 3.0 (0.33 to 19.0) |
| Rothia aeria a | 2.4 (0.37 to 7.6) | 0.52 (0.004 to 1.7) |
| Corynebacterium matruchotii a | 2.0 (0.66 to 5.4) | 0.85 (0.13 to 5.4) |
| Actinomyces naeslundii a | 1.8 (0.68 to 6.2) | 0.67 (0.15 to 5.7) |
| Rothia dentocariosa | 1.7 (0.12 to 24.5) | 0.70 (0.16 to 5.5) |
| Abiotrophia defectiva | 1.1 (0.07 to 6.3) | 1.3 (0.003 to 5.7) |
| Gemella haemolysans | 0.87 (0.09 to 3.8) | 1.2 (0.15 to 5.3) |
| Granulicatella adiacens | 0.82 (0.14 to 2.3) | 1.1 (0.02 to 2.4) |
| Porphyromonas HOT 279 | 0.63 (0.03 to 3.5) | 1.1 (0.02 to 8.4) |
| Granulicatella elegans a | 0.32 (0.03 to 1.2) | 1.0 (0.003 to 4.0) |
| Leptotrichia HOT 225 | 1.0 (0.03 to 4.5) | 0.45 (0.008 to 5.9) |
| Fusobacterium nucleatum ss. vincentii | 0.54 (0.04 to 3.8) | 0.88 (0.09 to 4.1) |
| Corynebacterium durum | 0.80 (0.14 to 9.4) | 0.41 (0 to 4.3) |
| Streptococcus mutans | 0.15 (0.006 to 10.4) | 0.73 (0.02 to 22.9) |
| Prevotella melaninogenica a | 0.10 (0.002 to 3.6) | 0.71 (0.03 to 11.8) |
| Alloprevotella HOT 473a | 0.04 (0 to 1.7) | 0.69 (0.001 to 9.3) |
| Gemella morbillorum | 0.58 (0.11 to 3.3) | 0.69 (0.07 to 2.0) |
| Haemophilus HOT 036a | 0.07 (0.003 to 0.3) | 0.56 (0.001 to 3.5) |
| Streptococcus sanguinis a | 0.56 (0.19 to 0.8) | 0.28 (0.13 to 0.7) |
| Neisseria mucosa | 0.44 (0.09 to 1.2) | 0.34 (0.02 to 1.2) |
| Aggregatibacter HOT 458 | 0.25 (0.003 to 2.3) | 0.43 (0.05 to 2.8) |
| Genera level | ||
| Streptococcus | 28.3 (16.8 to 49.6) | 31.3 (12.8 to 50.0) |
| Leptotrichia a | 10.5 (4.2 to 23.7) | 5.7 (0.61 to 30.4) |
| Neisseria | 7.5 (0.70 to 27.9) | 9.0 (0.22 to 26.4) |
| Rothia a | 4.8 (0.72 to 29.9) | 1.7 (0.04 to 10.3) |
| Fusobacterium | 4.8 (0.65 to 12.3) | 3.7 (1.1 to 9.5) |
| Haemophilus | 2.1 (0.01 to 7.5) | 4.6 (0.13 to 12.8) |
| Veillonella | 2.4 (0.18 to 10.1) | 4.1 (0.39 to 19.8) |
| Corynebacterium a | 3.3 (1.4 to 14.8) | 1.6 (0.01 to 8.1) |
| Actinomyces a | 3.2 (1.4 to 9.4) | 1.8 (0.25 to 7.4) |
| Lautropia | 3.2 (0.19 to 11.6) | 2.2 (0.05 to 10.2) |
| Prevotella | 0.93 (0.17 to 9.1) | 2.5 (0.20 to 26.5) |
| Granulicatella | 1.3 (0.22 to 2.6) | 2.3 (0.06 to 5.7) |
| Gemella | 1.6 (0.20 to 4.9) | 2.0 (0.29 to 7.0) |
| Porphyromonas | 1.3 (0.08 to 5.1) | 1.8 (0.023 to 9.2) |
| Capnocytophaga | 1.5 (0.48 to 5.1) | 0.94 (0.19 to 2.7) |
| Abiotrophia | 1.1 (0.07 to 6.3) | 1.3 (0.003 to 5.7) |
| Kingella | 1.2 (0.61 to 2.5) | 0.80 (0.065 to 2.1) |
| Alloprevotella a | 0.13 (0.003 to 1.7) | 1.0 (0.006 to 9.5) |
| Aggregatibacter | 0.88 (0.01 to 3.3) | 0.99 (0.14 to 4.1) |
| Campylobacter | 0.59 (0.14 to 2.5) | 0.46 (0.08 to 3.9) |
| Selenomonas | 0.29 (0.02 to 3.7) | 0.54 (0.02 to 4.2) |
| Cardiobacterium a | 0.45 (0.04 to 2.2) | 0.17 (0.002 to 0.7) |
| Lachnoanaerobaculum | 0.43 (0.16 to 2.6) | 0.32 (0.03 to 1.6) |
| TM7 [G-1]a | 0.33 (0.004 to 1.4) | 0.11 (0.005 to 1.8) |
| Bergeyella | 0.33 (0.03 to 0.8) | 0.27 (0.05 to 1.2) |
HOT, Human Oral Taxon; OTU, operational taxonomic unit; S-ECC, severe early childhood caries.
a
P ≤ 0.05, Kruskal-Wallis test, corrected for multiple comparisons by the false discovery rate method.