. 2017 Oct 17;10:5031–5046. doi: 10.2147/OTT.S145949

Table S1.

Correlations between epithelial-to-mesenchymal transition/cancer stem cell markers and clinicopathological characteristics

Characteristics	Total	E-cadherin		p-value	Total	N-cadherin		p-value	Total	Sox-2		p-value	Total	Oct-4		p-value	Total	Nanog		p-value
Characteristics	Total	Low	High	p-value	Total	Low	High	p-value	Total	Low	High	p-value	Total	Low	High	p-value	Total	Low	High	p-value
Gender				0.761				0.892				0.621				0.279				0.434
Female	122	74	48		122	60	62		122	69	53		122	72	50		122	86	36
Male	158	93	65		158	79	79		158	94	64		158	83	75		158	118	40
Age				0.960				0.607				0.878				0.892				0.559
≤65 years	111	66	45		111	53	58		111	64	47		111	62	49		111	83	28
>65 years	169	101	68		169	86	83		169	99	70		169	93	76		169	121	48
Tumor location				0.708				0.117				0.748				0.803				0.538
Rectal	130	76	54		130	58	72		130	77	53		130	73	57		130	97	33
Colon	150	91	59		150	81	69		150	86	64		150	82	68		150	107	43
Tumor size				0.297				0.233				0.904				0.664				0.731
≤5 cm	214	124	90		214	102	112		214	125	89		214	120	94		214	157	57
>5 cm	66	43	23		66	37	29		66	38	28		66	35	31		66	47	19
Tumor differentiation				0.555				0.311				0.422				0.992				0.134
Poor	74	42	32		74	33	41		74	46	28		74	41	33		74	49	25
Well/moderate	206	125	81		206	106	100		206	117	89		206	114	92		206	155	51
Tumor invasion				0.275				0.555				0.630				0.120				0.010
T1–T2	96	53	43		96	50	46		96	54	42		96	47	49		96	79	17
T3–T4	184	114	70		184	89	95		184	109	75		184	108	76		184	125	59
Lymph node metastasis				0.029				0.024				0.046				0.609				0.003
N1	81	39	42		81	31	50		81	43	38		81	45	36		81	59	22
N2a	95	58	37		95	56	39		95	65	30		95	56	39		95	80	15
N2b	104	70	34		104	52	52		104	55	49		104	54	50		104	65	39
Distant metastasis				0.039				0.012				0.396				<0.001				0.118
Absent	218	123	95		218	117	101		218	124	94		218	134	84		218	154	64
Present	62	44	18		62	22	40		62	39	23		62	21	41		62	50	12
Ki-67 positivity				0.042				0.382				0.483				0.394				0.041
<30%	78	54	24		78	42	36		78	48	30		78	40	38		78	50	28
≥30%	202	113	89		202	97	105		202	115	87		202	115	87		202	154	48
Serum CEA level				0.199				0.971				0.174				0.764				0.276
≤5 ng/mL	99	54	45		99	49	50		99	63	36		99	56	43		99	76	23
>5 ng/mL	181	113	68		181	90	91		181	100	81		181	99	82		181	128	53
BMI				0.472				0.887				0.367				0.394				0.166
<18.5 kg/m²	22	12	10		22	12	10		22	14	8		22	11	11		22	13	9
18.5–24.99 kg/m²	178	111	67		178	88	90		178	98	80		178	104	74		178	128	50
≥25.0 kg/m²	80	44	36		80	39	41		80	51	29		80	40	40		80	63	17

Abbreviations: CEA, carcinoembryonic antigen; BMI, body mass index.