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. 2017 Aug 4;38(4):1949–1958. doi: 10.3892/or.2017.5882

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Copyright: © Meryet-Figuière et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Schedules for in vivo siRNA treatments. (A) Mice were injected i.p. with 20×10⁶ SKOV3-Luc cells and tumors were allowed to develop for 4 weeks. Bioluminescence values were acquired at day 0 prior to treatment, day 3 and 7. Atelocollagen (0.5% final) in complex with 100 µg siRNA was injected i.p. at day 0 and 2. (B) Mice were injected bilaterally s.c. with 5×10⁶ SKOV3-Luc cells in each flank and tumors were allowed to develop for 4 weeks. Bioluminescence values were acquired at day 0 prior to treatment, day 3 and 7. Atelocollagen (0.05% final) in complex with 125 µg siRNA was injected i.p. at days 0, 1 and 2.