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. 2017 Aug 25;38(4):2023–2032. doi: 10.3892/or.2017.5923

Figure 4.

Figure 4.

Effects of GNL3 knockdown and overexpression on cell invasion and migration in vitro. (A) Following GNL3 knockdown (GNL3 shRNA), the invasive capacity of HCT-116 cells was decreased compared with those of control cells (Con). Following GNL3 overexpression (GNL3), the invasive capacity of HT-29 cells was increased compared with negative control cells (NC). (B) GNL3 knockdown inhibited the migration of HCT-116 cells, and GNL3 overexpression promoted the migration of HT-29 cells. *P<0.05 and **P<0.01; Student's t-test. GNL3, G protein nucleolar 3.