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. 2017 Aug 3;38(4):2003–2010. doi: 10.3892/or.2017.5877

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Copyright: © Guo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — FOXQ1 is involved in EMT of GC cells induced by co-culture with TAMs. (A and B) Co-culture with THP-1 cells significantly increased the expression of FOXQ1 at both the mRNA and protein levels of MKN45 and MKN74 cells. (C and D) Transfection with shRNA targeting FOXQ1 resulted in the pronounced knockdown of mRNA and protein levels in MKN45 and MKN74 cells. Values are depicted as the mean ± SD; *P<0.05. FOXQ1, forkhead box Q1; EMT, epithelial-mesenchymal transition; GC, gastric cancer; TAMs, tumor-associated macrophages.