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. 2017 Aug 14;38(4):2011–2022. doi: 10.3892/or.2017.5908

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Aurora A silencing leads to reduced invasion in the MCF-7/T cells. (A and B) MCF-7/T cells showed higher invasion compared to the parent MCF-7/C cells in both regular MCF-7 cell lines and xenograft-originated MCF-7 cells [MCF-7(vivo) and MCF-7/T(vivo)]. Error bars represent standard deviation. ***P<0.001 indicated statistically significant divergence from the parent cells MCF-7/C; ^#P<0.05 indicated statistically significant divergence from the parent cells MCF-7/C(vivo). (C and D) Aurora A microRNA-treated MCF-7/T cells presented lower invasion compared to the control microRNA-treated ones. Error bars represented the standard deviation and an asterisk indicates statistically significant divergence from the negative control clones; **P<0.01, ***P<0.001.