Table I.

Correlation analyses of BZW2 protein expression in relation to clinicopathological variables of 50 patients with osteosarcoma.

		BZW2 expression level
Clinicopatho-logical parameters	No. of cases	Negative	Positive	χ2	P-value
Sex				1.602	0.206
Male	29	19	10
Female	21	10	11
Age (years)				0.512	0.474
<18	28	15	13
≥18	22	14	8
Location				1.667	0.434
Femur	24	12	12
Tibia	14	10	4
Elsewhere	12	7	5
Tumor necrosis rate (%)				0.006	0.939
<90	36	21	15
≥90	14	8	6
Cortical destruction				0.487	0.485
Yes	38	21	17
No	12	8	4
Recurrence				6.226	0.013a
Yes	23	9	14
No	27	20	7
Metastasis				0.112	0.738
Yes	32	18	14
No	18	11	7
Ennecking stage				6.912	0.009a
II	34	24	10
III	16	5	11

^aP<0.05. BZW2, basic leucine zipper and W2 domains 2.