Table I.
Expression of miR-195 | Expression of DCUN1D1 | ||||||||
---|---|---|---|---|---|---|---|---|---|
Parameters | n | Low (n, %) | High (n, %) | χ2 | P-value | Low (n, %) | High (n, %) | χ2 | P-value |
Age (years) | |||||||||
≤60 | 69 | 35 (50.7) | 34 (49.3) | 0.033 | 0.855 | 33 (47.8) | 36 (52.2) | 0.078 | 0.780 |
>60 | 53 | 26 (49.1) | 27 (50.9) | 24 (45.3) | 29 (54.7) | ||||
Sex | |||||||||
Female | 42 | 22 (52.4) | 20 (47.6) | 0.145 | 0.703 | 19 (45.2) | 23 (54.8) | 0.057 | 0.812 |
Male | 80 | 39 (48.8) | 41 (51.2) | 38 (47.5) | 42 (52.5) | ||||
Primary site | |||||||||
Glottis | 61 | 31 (50.8) | 30 (49.2) | 0.871 | 0.647 | 22 (36.1) | 39 (63.9) | 6.917 | 0.031 |
Supraglottis | 42 | 19 (45.2) | 23 (54.8) | 22 (52.4) | 20 (47.6) | ||||
Subglottis | 19 | 11 (57.9) | 8 (42.1) | 13 (68.4) | 6 (31.6) | ||||
Differentiation level | |||||||||
High | 77 | 38 (49.4) | 39 (50.6) | 0.035 | 0.851 | 33 (42.9) | 44 (57.1) | 1.252 | 0.263 |
Medium-low | 45 | 23 (51.1) | 22 (48.9) | 24 (53.3) | 21 (46.7) | ||||
T stage | |||||||||
T1+T2 | 30 | 1 (3.3) | 29 (96.7) | <0.001a | 20 (66.7) | 10 (33.3) | 6.358 | 0.012 | |
T3+T4 | 92 | 60 (65.2) | 32 (34.8) | 37 (40.2) | 55 (59.8) | ||||
Lymph node metastases | |||||||||
N0 | 81 | 35 (43.2) | 46 (56.8) | 4.445 | 0.035 | 54 (66.7) | 27 (33.3) | <0.001a | |
N+ | 41 | 26 (63.4) | 15 (36.6) | 3 (7.3) | 38 (92.7) | ||||
Distant metastasis | |||||||||
M0 | 118 | 57 (48.3) | 61 (51.7) | 0.059a | 57 (48.3) | 61 (51.7) | 0.077a | ||
M1 | 4 | 4 (100.0) | 0 (0.0) | 0 (0.0) | 4 (100.0) | ||||
Clinical stage | |||||||||
I+II | 23 | 1 (4.3) | 22 (95.7) | <0.001a | 18 (78.3) | 5 (21.7) | 11.326 | 0.001 | |
III+IV | 99 | 60 (60.6) | 39 (39.4) | 39 (39.4) | 60 (60.6) | ||||
Preoperative smoking | |||||||||
No | 23 | 15 (65.2) | 8 (34.8) | 2.625 | 0.105 | 8 (34.8) | 15 (65.2) | 1.623 | 0.203 |
Yes | 99 | 46 (46.5) | 53 (53.5) | 49 (49.5) | 50 (50.5) |
Fisher's exact test.