Table I.

Correlation between miR-195, DCUN1D1 expression and clinicopathological parameter in 122 LSCC patients.

		Expression of miR-195				Expression of DCUN1D1
Parameters	n	Low (n, %)	High (n, %)	χ2	P-value	Low (n, %)	High (n, %)	χ2	P-value
Age (years)
≤60	69	35 (50.7)	34 (49.3)	0.033	0.855	33 (47.8)	36 (52.2)	0.078	0.780
>60	53	26 (49.1)	27 (50.9)			24 (45.3)	29 (54.7)
Sex
Female	42	22 (52.4)	20 (47.6)	0.145	0.703	19 (45.2)	23 (54.8)	0.057	0.812
Male	80	39 (48.8)	41 (51.2)			38 (47.5)	42 (52.5)
Primary site
Glottis	61	31 (50.8)	30 (49.2)	0.871	0.647	22 (36.1)	39 (63.9)	6.917	0.031
Supraglottis	42	19 (45.2)	23 (54.8)			22 (52.4)	20 (47.6)
Subglottis	19	11 (57.9)	8 (42.1)			13 (68.4)	6 (31.6)
Differentiation level
High	77	38 (49.4)	39 (50.6)	0.035	0.851	33 (42.9)	44 (57.1)	1.252	0.263
Medium-low	45	23 (51.1)	22 (48.9)			24 (53.3)	21 (46.7)
T stage
T1+T2	30	1 (3.3)	29 (96.7)		<0.001a	20 (66.7)	10 (33.3)	6.358	0.012
T3+T4	92	60 (65.2)	32 (34.8)			37 (40.2)	55 (59.8)
Lymph node metastases
N0	81	35 (43.2)	46 (56.8)	4.445	0.035	54 (66.7)	27 (33.3)		<0.001a
N+	41	26 (63.4)	15 (36.6)			3 (7.3)	38 (92.7)
Distant metastasis
M0	118	57 (48.3)	61 (51.7)		0.059a	57 (48.3)	61 (51.7)		0.077a
M1	4	4 (100.0)	0 (0.0)			0 (0.0)	4 (100.0)
Clinical stage
I+II	23	1 (4.3)	22 (95.7)		<0.001a	18 (78.3)	5 (21.7)	11.326	0.001
III+IV	99	60 (60.6)	39 (39.4)			39 (39.4)	60 (60.6)
Preoperative smoking
No	23	15 (65.2)	8 (34.8)	2.625	0.105	8 (34.8)	15 (65.2)	1.623	0.203
Yes	99	46 (46.5)	53 (53.5)			49 (49.5)	50 (50.5)

^aFisher's exact test.