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. 2017 Oct 1;23(19-20):1142–1151. doi: 10.1089/ten.tea.2016.0503

FIG. 7.

FIG. 7.

Cytokine release. Cytokine release profiles after 5 h of testing. Significant increase of the proinflammatory cytokines, TNFα, IL-6, and IL-1α, in the tissue constructs without scaffold remnants. MCP-1 is upregulated in both tissue-engineered constructs. MMP-1 is significantly upregulated only in the tissue construct that does contain scaffold remnants, indicative of active cell infiltration. IL, interleukin; TNFα, tumor necrosis factor alpha; MCP-1, monocyte chemotactic protein 1; MMP-1, matrix metalloproteinase.