Incorporation of biomolecules by biomimetic mineralization. To further functionalize the coating created by SBFs, proteins, drugs, or genes can be incorporated into the apatite coatings. In this study, the ions present in SBF are displayed alongside the different therapeutic molecules that can be incorporated into the apatite coating of the substrate. BMP, bone morphogenetic protein; FGF, fibroblast growth factor; IGF, insulin-like growth factor. Color images available online at www.liebertpub.com/tea