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. 2017 Oct 23;12(10):e0185097. doi: 10.1371/journal.pone.0185097

Fig 5. Disease parameters in anti-miR-142-5p-treated mice.

Fig 5

Disease parameters in RAG1-/- mice treated with anti-miR-142-5p. (A) Survival of colitic mice treated with anti-miR-142-5p or the scrambled LNA-antagomir (control). Mice treated with anti-miR-142-5p show an improved survival. Log-Rank: P = 0.0026. (B) Body weight loss is less in anti-miR-142-5p-treated mice. (C) Disease activity index at death or sacrifice is significantly lower in anti-miR-142-5p-treated mice. (D) Ratio of colon weight corrected for mouse weight. Geometric mean with 95% confidence interval. (E) Histology score at death or sacrifice is significantly lower in anti-miR-142-5p-treated mice.