Table 1. Locked nucleic acid (LNA) oligonucleotide sequences.

Compound	Sequence (5’-3’)	Purity
Scrambled LNA	5’-C a u G u g C u g C u a A c a A u u T a c C	>95%
Anti-miR-203	5’-C u a G u g G u c C u a A a c A u u T c a C	>95%
Anti-miR-146B	5’-A g c C u a T g g A a u T c a G u u C u c A	>95%
Anti-miR-142-5p	5’-A g u A g u G c u T u c T a c T u u A u G	>95%
Anti-miR-223	5’-T g g G g u A u u T g s C a a A c u G a c A	>95%

The four most significantly upregulated miRNAs in transfer colitic mice versus transfer non-colitic mice were selected, and anti-miRNA LNA sequences and a scrambled LNA sequence were created for use in further experiments. LNA moieties are capitalized, while lowercase bases are 2’OMeRNA.