Table 4. Differentially expressed miRNAs in colon.
Time point 1 | Time point 2 | Time point 3 | ||||
---|---|---|---|---|---|---|
miRNA | FC | P-value | FC | P-value | FC | P-value |
MIR-223 | 2.00 | 0.21 | 2.50 | 0.10 | 11.63 | 0.0003 |
MIR-142-5P | 1.17 | 0.81 | 3.29 | 0.08 | 11.31 | 0.0019 |
MIR-146B-5P | 2.60 | 0.16 | 2.36 | 0.20 | 10.70 | 0.0023 |
MIR-203 | 1.77 | 0.35 | 1.66 | 0.40 | 7.57 | 0.0041 |
MIR-18A | 1.89 | 0.32 | 3.07 | 0.09 | 7.21 | 0.0064 |
MIR-7 | 1.14 | 0.82 | 2.19 | 0.18 | 5.43 | 0.0089 |
MIR-20A | 1.54 | 0.44 | 1.54 | 0.44 | 4.92 | 0.010 |
MIR-142-3P | 2.89 | 0.10 | 2.99 | 0.09 | 4.86 | 0.018 |
MIR-21 | 1.03 | 0.96 | 2.07 | 0.16 | 3.46 | 0.024 |
MIR-17 | 1.87 | 0.29 | 1.84 | 0.30 | 3.89 | 0.030 |
MIR-146A | 1.67 | 0.46 | 4.26 | 0.05 | 4.41 | 0.046 |
Fold change (FC) of miRNA expression in colon of mice with CD45RBhi transfer colitis versus non-colitic mice, at three different time points during colitis development. All 11 miRNAs with p<0.05 at time point 3 are listed.