Table 2.
Odds ratios for penalized logistic regression models
| Covariate | Mucositis model
|
Dysphagia model
|
||
|---|---|---|---|---|
| Odds ratio | 95% CI | Odds ratio | 95% CI | |
| Intercept | 2.512 | 0.016-12.43 | 0.360 | 0.007-2.583 |
| Male | 1.000 | 1.000-2.554 | 1.000 | 1.000-1.945 |
| Age | 1.000 | 0.971-1.006 | 1.000 | 0.980-1.000 |
| Definitive RT | 1.000 | 0.110-1.000 | 1.000 | 0.544-1.000 |
| Induction chemotherapy | 1.000 | 0.410-1.166 | 1.000 | 1.000-2.089 |
| Cisplatin | 1.000 | 1.000-3.464 | 1.277 | 1.000-3.230 |
| Carboplatin | 1.000 | 0.361-4.015 | 1.000 | 1.000-4.278 |
| Cis-carbo | 1.000 | 0.136-1.769 | 1.000 | 0.989-2.930 |
| Hypopharynx or larynx | 1.000 | 1.000-14.71 | 1.000 | 1.000-2.203 |
| Nasopharynx or nasal cavity | 1.000 | 0.905-6.190 | 1.000 | 0.247-1.000 |
| Unknown primary | 1.000 | 0.022-1.000 | 1.000 | 0.945-1.210 |
| Parotid | 0.814 | 0.231-2.546 | 0.600 | 0.208-1.000 |
| V020 | 1.000 | 1.000-1.119 | 1.000 | 1.000-1.031 |
| V040 | 1.000 | 0.891-1.000 | 1.000 | 1.000-1.014 |
| V060 | 1.000 | 1.000-1.032 | 1.000 | 1.000-1.003 |
| V080 | 1.000 | 1.000-1.050 | 1.000 | 1.000-1.023 |
| V100 | 1.000 | 0.934-1.000 | 1.000 | 1.000-1.029 |
| V120 | 1.000 | 1.000-1.084 | 1.019 | 1.000-1.044 |
| V140 | 1.000 | 0.917-1.000 | 1.000 | 1.000-1.019 |
| V160 | 1.000 | 1.000-1.038 | 1.000 | 1.000-1.011 |
| V180 | 1.002 | 1.000-1.085 | 1.000 | 0.997-1.009 |
| V200 | 1.000 | 0.949-1.007 | 1.000 | 1.000-1.019 |
| V220 | 1.000 | 1.000-1.098 | 1.008 | 1.000-1.031 |
| V240 | 1.000 | 0.616-1.154 | 1.000 | 1.000-1.025 |
| V260 | 1.000 | 1.000-1.000 | 1.000 | 1.000-1.000 |
Abbreviations: Cis-carbo = 1 cycle of cisplatin followed by 1 cycle of carboplatin; RT = radiation therapy; 95% CI = 95% confidence interval calculated by bootstrapping model fitting with 2000 replicates; Vx = volume of organ receiving x cGy of radiation per fraction.