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. 2017 Oct 23;12(10):e0186395. doi: 10.1371/journal.pone.0186395

Table 1. Mass isotopomer distribution of the TCA cycle intermediates.

Metabolite M+0 (SD) M+1 (SD) M+2 (SD) M+3 (SD) M+4 (SD)
Citrate 33% ±1.53 17% ±1.56 24% ±1.45 18% ±1.1 8% ±1.13
2-Oxoglutarate 47% ±0.15 12% ±0.34 25% ±1.23 11% ±0.22 6% ±1.99
Succinyl-CoA 50% ±2.08 14% ±1.68 19% ±3.08 12% ±2.73 5% ±1.69
Succinate 50% ±0.09 15% ±0.14 10% ±1.21 21% ±0.22 4% ±1.09
Fumarate 47% ±0.15 20% ±0.48 16% ±0.18 17% ±0.74
Malate 45% ±0.05 21% ±0.43 15% ±0.02 17% ±0.33

For GC/MS data n = 3, for HPLC/MS data (Succinyl-CoA) n = 4. Not determined mass isotopologue fractions are not displayed. SD = relative standard deviation.