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. 2017 Oct 23;12(10):e0186791. doi: 10.1371/journal.pone.0186791

Table 2. Levels of inhibition of the mRNA and protein expression of viral genes in cells expressing ribozymes, as compared to the levels of inhibition in cells that did not express a ribozyme (U251).

The values are derived from experiments that were performed in triplicate and repeated three times. The values of standard deviation for these results are less than 5%.

Viral gene Gene class U251 C-M1-IE C-R228-IE F-M1-IE F-R228-IE F-M1-TK
IE1 mRNA IE 0% 6% 8% 77±7% 99±9% 0%
IE2 mRNA IE 0% 5% 7% 79±7% 98±8% 0%
US2 mRNA Early 0% 2% 2% 78±6% 98±9% 0%
IE1 protein IE 0% 5% 7% 77±7% 99±8% 0%
IE2 protein IE 0% 5% 6% 78±8% 98±9% 0%
UL99 protein Late 0% 0% 0% 79±7% 98±8% 0%