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. 2017 Oct 23;12(10):e0186960. doi: 10.1371/journal.pone.0186960

Table 2. Validation results from each step of the generation process of a pediatric mature B cell non-Hodgkin lymphoma cohort.

True positives False positives False negatives Sensitivity (95% CI) Positive predictive value (95% CI)
Step 1: Identification via ICD-9 codes (200.0, 200.2, 200.5, 200.7, 200.8, 202.8, 202.9) 103 70 5 95.4% (89.5–98.5%) 59.5% (51.8–66.9%)
Step 2: Manual chemotherapy review* 97 5 9 91.5% (84.5–96.0%) 95.1% (88.9% - 98.4%)

*The validation cohort for sensitivity and PPV calculations included 178 patients aged 0–21 treated at CHOP during the study period.