Table 2. Validation results from each step of the generation process of a pediatric mature B cell non-Hodgkin lymphoma cohort.
True positives | False positives | False negatives | Sensitivity (95% CI) | Positive predictive value (95% CI) | |
---|---|---|---|---|---|
Step 1: Identification via ICD-9 codes (200.0, 200.2, 200.5, 200.7, 200.8, 202.8, 202.9) | 103 | 70 | 5 | 95.4% (89.5–98.5%) | 59.5% (51.8–66.9%) |
Step 2: Manual chemotherapy review* | 97 | 5 | 9 | 91.5% (84.5–96.0%) | 95.1% (88.9% - 98.4%) |
*The validation cohort for sensitivity and PPV calculations included 178 patients aged 0–21 treated at CHOP during the study period.