Table 2. Average dice coefficients, sensitivity and precision of the proposed method in Optima dataset.

		GC [43]			KGC [44]			Method in [31]			Method in [52]			Method in [53]			Prop. Method
	Sub	E.1	E. 2	Ave.	E.1	E. 2	Ave.	E.1	E. 2	Ave.	E. 1	E. 2	Ave.	E. 1	E. 2	Ave.	Expr.1	Expr. 2	Ave.
Dice Coeff.	1	73.49	72.96	73.22	80.43	79.10	79.76	71.40	68.17	69.78	61	56	58.5	72	76	74	82.96	82.90	83.02
	2	73.90	71.68	72.79	55.10	55.11	55.10	45.49	45.81	45.65	79	76	77.5	84	84	84	78.11	79.09	77.13
	3	78.46	82.33	80.40	75.35	79.34	77.35	69.54	65.01	67.27	43	42	42.5	72	75	73.5	82.23	80.36	84.10
	4	78.12	77.91	78.01	71.78	71.56	71.67	71.15	72.55	71.85	46	45	45.5	64	67	65.5	80.75	80.87	80.63
	Ave.	75.99	76.22	76.10	70.66	71.27	70.97	64.39	62.88	63.63	57.25	54.75	56	73	75.5	74.25	81.01	80.80	81.22
Sensitivity	1	70.81	69.95	70.38	82.19	78.56	80.37	72.49	66.75	69.62	NA	NA	NA	NA	NA	NA	84.43	80.94	82.68
	2	96.79	92.25	94.52	99.04	94.54	96.79	70.45	64.71	67.58	NA	NA	NA	NA	NA	NA	98.94	94.45	96.70
	3	75.72	81.49	78.60	85.13	90.95	88.04	47.38	54.84	51.11	NA	NA	NA	NA	NA	NA	85.18	90.75	87.96
	4	78.78	78.54	78.66	80.59	80.22	80.40	77.79	77.56	77.67	NA	NA	NA	NA	NA	NA	84.49	83.70	84.09
	Ave.	80.52	80.55	80.54	86.73	86.06	86.40	67.02	65.96	66.49	NA	NA	NA	NA	NA	NA	88.26	87.46	87.85
Precision	1	93.00	95.71	94.36	85.06	86.55	85.81	54.87	59.61	57.24	NA	NA	NA	NA	NA	NA	84.03	87.53	85.78
	2	74.36	74.45	74.40	54.18	54.14	54.16	51.12	51.34	51.23	NA	NA	NA	NA	NA	NA	78.48	78.58	78.53
	3	94.89	96.10	95.49	79.88	79.96	79.92	30.93	37.99	34.46	NA	NA	NA	NA	NA	NA	85.45	85.48	85.47
	4	96.97	97.24	97.11	88.62	88.99	88.81	54.98	59.50	57.24	NA	NA	NA	NA	NA	NA	93.20	93.58	93.39
	Ave.	89.80	90.87	90.34	76.93	77.41	77.17	47.97	52.11	50.04	NA	NA	NA	NA	NA	NA	85.29	86.29	85.79