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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Neurobiol Aging. 2017 Sep 5;60:153–163. doi: 10.1016/j.neurobiolaging.2017.08.027

Table 2.

Regions that increased or decreased significantly to increasing working memory load

A. Positive modulation to difficulty effect
Cluster Label BA k X Y Z t-value Cluster-Level p fwe
L/R posterior parietal/precuneus 39/40/7 4731 42 −42 42 19.57 < .001
−39 −48 42 18.94
33 −66 39 18.90

L/R frontal/subcortical/cerebellum 6/9 16431 −30 −63 −33 17.64 < .001
30 −63 −33 16.94
33 12 54 16.74
B. Negative modulation to difficulty effect
Cluster Label BA k X Y Z t-value Cluster-Level p fwe
L/R medial cortex/temporal 10/20/47 18456 −3 60 3 14.57 < .001
−6 −51 27 13.09
45 −27 21 11.59

Note. The Statistical nonParametric Mapping toolbox v13 (SnPM) was used to calculate cluster thresholds. Abbreviations: BA – Brodmann Area; L – Left; R – Right