Table 3.

Regions of effect of age on increasing parametric WM Load

A. Age-Related Decreases in Positive Modulation to WM Load
Cluster Label	BA	k	X	Y	Z	t-value	Cluster-Level p fwe
R middle frontal gyrus	6/8	224	33	3	60	5.90	0.010
R angular gyrus	39	319	33	−69	51	5.07	0.006
			36	−51	45	4.86
L angular gyrus	39	96	−33	−54	48	4.18	0.046
			−27	−60	39	3.96
			−30	−66	54	3.75
L supplementary motor area	6	117	0	18	48	4.17	0.034
			0	6	63	3.61

B. Age-Related Decreases in Negative Modulation to WM Load
Cluster Label	BA	k	X	Y	Z	t-value	Cluster-Level p fwe
R fusiform gyrus	37	281	24	−39	−12	6.54	0.010
			24	−72	−9	4.29
L fusiform gyrus	37	203	−24	−42	−12	6.43	0.015
			−39	−21	−15	3.88
L angular gyrus	39	844	−48	−75	30	6.00	0.002
			−15	−93	36	5.51
			−30	−84	15	4.65
R middle occipital gyrus	19	872	30	−90	24	5.69	0.002
			39	−72	6	5.67
			21	−93	36	5.50
L superior frontal gyrus	9/10	636	−3	60	6	4.95	0.002
			−15	45	45	4.86
			−3	54	27	4.51
R hippocampus		117	39	−6	−15	4.80	0.035
			30	−9	−18	4.55
L precuneus/lingual gyrus	31	127	−12	−54	12	4.79	0.030
			−9	−51	3	3.90
			0	−51	21	3.24
R insula	13	165	42	−9	18	4.65	0.022
			51	−3	3	3.82
R/L precuneus	31	127	12	−42	54	4.26	0.030
			−12	−42	54	3.96
L/R middle cingulate gyrus	24	167	3	−6	39	3.97	0.022
			−3	3	36	3.91
			−9	−6	30	3.34
R precentral gyrus	6	108	45	−15	66	3.75	0.04
			39	−6	−15	4.80
			24	−6	−15	3.92

Note. The Statistical nonParametric Mapping toolbox v13 (SnPM) was used to calculate cluster thresholds. Abbreviations: BA – Brodmann Area; L – left; R – Right