Table 1.
HR = heart rate; IVSd = diastolic interventricular septum thickness; LVIDs = systolic left ventricular internal dimension; LVIDd = diastolic left ventricular internal dimension; FS = left ventricular fractional shortening; LVM = left ventricular mass; LVPWd = diastolic left ventricular posterior wall thickness.
Before CLP | After CLP | |||
---|---|---|---|---|
Non-obese | Obese | Non-obese | Obese | |
HR (bpm) | 442 ± 85 | 437 ± 24 | 325 ± 46* | 430 ± 25# |
IVSd (mm) | 0.85 ± 0.1 | 0.78 ± 0.02 | 1 ±0.16 | 0.86 ± 0.15 |
LVIDs (mm) | 2.53 ± 0.35 | 3.17 ± 0.41# | 2.27 ± 0.85 | 2.54 ± 0.34* |
LVIDd (mm) | 4 ± 0.41 | 4.20 ± 0.35 | 3.51 ± 0.76 | 3.68 ± 0.4* |
FS (%) | 34 ±4 | 25 ± 5# | 37 ± 10 | 31 ± 4* |
LVM (mg) | 96 ± 14.1 | 95.2 ± 14.8 | 91 ± 8 | 84 ± 7* |
LVPWd (mm) | 0.74 ± 0.07 | 0.73 ± 0.1 | 0.88 ± 0.23 | 0.77 ± 0.07 |
HR = heart rate; IVSd = diastolic interventricular septum thickness; LVIDs = systolic left ventricular internal dimension; LVIDd = diastolic left ventricular internal dimension; F5 = left ventricular fractional shortening; LVM = left ventricular mass; LVPWd = diastolic left ventricular posterior wall thickness;.
p<0.05 versus non-obese by t-test,
p<0.05 versus before CLP by paired t-test. n=8 mice/group.