Table 2. Univariate analysis.

Variable	Colonna 1 (DFI)	P (OS)	Colonna 2 [survival after metastasectomies (all)]	Colonna 3 (survival after 1 single metastasectomy)
Gender	0.32	0.14	0.081	0.061
Age	0.31	0.29	0.34	0.051
Tumor location	0.13	0.13	0.20	0.04
Staging	0.17	0.13	0.096	0.27
Grading	0.27	0.35	0.39	0.46
Hystological type	0.83	0.57	0.17	0.20
Vessel invasion	0.60	0.61	0.49	0.90
Inflammatory infiltrate	0.49	0.53	0.74	0.65
Neoadjuvant chemotherapy	0.37	0.39	0.41	0.73
Adjuvant chemotherapy	0.50	0.30	0.16	0.83
Radiotherapy	0.26	0.17	0.14	0.43
Chemotherapy	0.61	0.42	0.18	0.68
CK7	0.71	0.75	0.67	0.45
CK20	0.43	0.33	0.3	0.321
>1 resected pulmonary metastases	0.0068	0.005	0.003	–

All variables have been compared considering disease free interval, overall survival, survival after metastasectomies (all patients) and survival after one single metastasectomy (only patients having one metastasis). DFI, disease free interval; OS, overall survival; CK7, cytokeratin 7; CK20, cytokeratin 20.