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. 2017 Apr 18;15(2):83–93. doi: 10.1016/j.aju.2017.03.005

Table 2.

Results of the 10 included studies.

Reference Treatment vs control Expulsion rate, n/N Expulsion time, days, mean (SD) unless otherwise specified Standard therapy Re-hospitalisation, n/N Side-effects
Al-Ansari et al. [25] Tamsulosin 41/50 6.4 (2.77) Diclofenac 1 retrograde ejaculation and 1 hypotension in tamsulosin group. Dizziness and headache 2 each in each group. 1 rhinitis in tamsulosin group. Fatigue 2 in tamsulosin group and 1 in control group
Control 28/46 9.87 (5.4)
Furyk et al. [26] Tamsulosin 140/161 Median 7 Indomethacin, oxycodone 20/198
23/193
Dizziness, tamsulosin 46, control 36; Palpitations, tamsulosin 13, control 14; Collapse, tamsulosin 3, control 2; Sexual dysfunction, tamsulosin 13, control 5; Headache, tamsulosin 50, control 56; Fatigue, tamsulosin 55, control 47; Nausea, tamsulosin 53, control 55; Vomiting, tamsulosin 14, control 18; Diarrhoea, tamsulosin 23, control 22; Constipation tamsulosin 36, control 28
Control 127/155 Median 11
Hermanns et al. [27] Tamsulosin 39/45 Median 7 Diclofenac, metamizole 6/45
2/45
Tamsulosin group: 1 diarrhoea, 1 cutaneous reaction, 2 retrograde ejaculation
Placebo group: 1 dizziness
Control 40/45 Median 10
Ochoa-Gomez et al. [28] Tamsulosin 22/32 22 (6.77) Not specified Tamsulosin group: 2 dizziness 2 retrograde ejaculation
Placebo 23/33 23 (6.36)
Pedro et al. [29] Alfuzosin 25/34 5.2 (4.82) None Alfuzosin 4 patients with dizziness and hypotension and stopped treatment. Nil in placebo
Control 27/35 8.5 (6.99)
Pickard et al. [30] Tamsulosin 307/378 16.5 (12.6), 79 patients Not clear Nifedipine 1 with diarrhoea, pain and vomiting, 1 with malaise, headache and chest pain. 1 with chest pain.
Placebo 1 with headache, pain, light-headedness
Nifedipine 304/379 16.2 (14.5), 74 patients
Control 303/379 15.9 (11.3), 84 patients
Control 22/30
Sameer et al. [31] Alfuzosin 30/35 12 (6.67) Diclofenac, tramadol 5/35
11/35
27/35
Alfuzosin 3 retrograde ejaculation
Nifedipine 1 hypotension
Nifedipine 21/35 12 (6.69)
Control 7/35 12.29 (9.46)
Sur et al. [32] Silodosin 60/115 Oxycodone Retrograde ejaculation, silodosin 11, control 1; Nausea, silodosin 9, control 2; Dizziness, silodosin 8, control 2; Headache, silodosin 4, control 0; Vomiting, silodosin 4, control 4; Constipation, silodosin 3, control 2; Nasal congestion, silodosin 3, control 0; Diarrhoea, silodosin 2, control 3
Control 52/117
Vincendeau et al. [33] Tamsulosin 47/61 10.1 (10) Ketoprofen and phloroglucinol 4/61
6/61
Headache, placebo 7 tamsulosin 7; Asthenia, placebo 18 tamsulosin 21; Orthostatic hypotension, placebo 3 tamsulosin 6; Palpitation, placebo 1 tamsulosin 3; Nausea or vomiting, placebo 7 tamsulosin 12; Other gastrointestinal disorder, placebo 10 tamsulosin 16; Retrograde ejaculation, tamsulosin 4; Skin reaction placebo 1
Placebo 43/61 9.6 (9.8)
Wang et al. [34] Silodosin 48/62 6.31 (2.13) Ketoroalic and buprenorphine 0/62
0/61
Silodosin 10, placebo 2: asthenia; hypotension; palpitation; syncope
Placebo 33/61 9.73 (2.76)