Table 2.
Reference | Treatment vs control | Expulsion rate, n/N | Expulsion time, days, mean (SD) unless otherwise specified | Standard therapy | Re-hospitalisation, n/N | Side-effects |
---|---|---|---|---|---|---|
Al-Ansari et al. [25] | Tamsulosin | 41/50 | 6.4 (2.77) | Diclofenac | 1 retrograde ejaculation and 1 hypotension in tamsulosin group. Dizziness and headache 2 each in each group. 1 rhinitis in tamsulosin group. Fatigue 2 in tamsulosin group and 1 in control group | |
Control | 28/46 | 9.87 (5.4) | ||||
Furyk et al. [26] | Tamsulosin | 140/161 | Median 7 | Indomethacin, oxycodone | 20/198 23/193 |
Dizziness, tamsulosin 46, control 36; Palpitations, tamsulosin 13, control 14; Collapse, tamsulosin 3, control 2; Sexual dysfunction, tamsulosin 13, control 5; Headache, tamsulosin 50, control 56; Fatigue, tamsulosin 55, control 47; Nausea, tamsulosin 53, control 55; Vomiting, tamsulosin 14, control 18; Diarrhoea, tamsulosin 23, control 22; Constipation tamsulosin 36, control 28 |
Control | 127/155 | Median 11 | ||||
Hermanns et al. [27] | Tamsulosin | 39/45 | Median 7 | Diclofenac, metamizole | 6/45 2/45 |
Tamsulosin group: 1 diarrhoea, 1 cutaneous reaction, 2 retrograde ejaculation Placebo group: 1 dizziness |
Control | 40/45 | Median 10 | ||||
Ochoa-Gomez et al. [28] | Tamsulosin | 22/32 | 22 (6.77) | Not specified | Tamsulosin group: 2 dizziness 2 retrograde ejaculation | |
Placebo | 23/33 | 23 (6.36) | ||||
Pedro et al. [29] | Alfuzosin | 25/34 | 5.2 (4.82) | None | Alfuzosin 4 patients with dizziness and hypotension and stopped treatment. Nil in placebo | |
Control | 27/35 | 8.5 (6.99) | ||||
Pickard et al. [30] | Tamsulosin | 307/378 | 16.5 (12.6), 79 patients | Not clear | Nifedipine 1 with diarrhoea, pain and vomiting, 1 with malaise, headache and chest pain. 1 with chest pain. Placebo 1 with headache, pain, light-headedness |
|
Nifedipine | 304/379 | 16.2 (14.5), 74 patients | ||||
Control | 303/379 | 15.9 (11.3), 84 patients | ||||
Control | 22/30 | – | ||||
Sameer et al. [31] | Alfuzosin | 30/35 | 12 (6.67) | Diclofenac, tramadol | 5/35 11/35 27/35 |
Alfuzosin 3 retrograde ejaculation Nifedipine 1 hypotension |
Nifedipine | 21/35 | 12 (6.69) | ||||
Control | 7/35 | 12.29 (9.46) | ||||
Sur et al. [32] | Silodosin | 60/115 | – | Oxycodone | Retrograde ejaculation, silodosin 11, control 1; Nausea, silodosin 9, control 2; Dizziness, silodosin 8, control 2; Headache, silodosin 4, control 0; Vomiting, silodosin 4, control 4; Constipation, silodosin 3, control 2; Nasal congestion, silodosin 3, control 0; Diarrhoea, silodosin 2, control 3 | |
Control | 52/117 | – | ||||
Vincendeau et al. [33] | Tamsulosin | 47/61 | 10.1 (10) | Ketoprofen and phloroglucinol | 4/61 6/61 |
Headache, placebo 7 tamsulosin 7; Asthenia, placebo 18 tamsulosin 21; Orthostatic hypotension, placebo 3 tamsulosin 6; Palpitation, placebo 1 tamsulosin 3; Nausea or vomiting, placebo 7 tamsulosin 12; Other gastrointestinal disorder, placebo 10 tamsulosin 16; Retrograde ejaculation, tamsulosin 4; Skin reaction placebo 1 |
Placebo | 43/61 | 9.6 (9.8) | ||||
Wang et al. [34] | Silodosin | 48/62 | 6.31 (2.13) | Ketoroalic and buprenorphine | 0/62 0/61 |
Silodosin 10, placebo 2: asthenia; hypotension; palpitation; syncope |
Placebo | 33/61 | 9.73 (2.76) |