Figure 4. Overall pooling for the fixed appliance (FA) treatment duration in months. Mean treatment durations and their corresponding 95% confidence intervals (CIs) for each included study are given as boxes with horizontal lines, respectively. The weighted pooled summary estimates with and their corresponding 95% CIs for the two subgroups or overall are given as diamonds. Horizontal lines at the diamonds represent the 95% prediction that gives a range of possible values to be clinically seen, while incorporating existing heterogeneity.