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. 2017 Oct 19;8:281. doi: 10.3389/fendo.2017.00281

Figure 1.

Figure 1

The effect of estradiol (E2) replacement and dietary S-equol on the time course of body weight change (Δ body weight) from the day of ovariectomy in ovariectomized rats. Rats were ovariectomized and assigned to the E2-replaced or cholesterol [vehicle (Veh)]-treated group. These rats were fed a standard (control) diet (ConD) or an S-equol-containing diet (EqD). Values are shown as the mean ± SEM (n = 10 in E2 + ConD; n = 10 in E2 + EqD; n = 11 in Veh + ConD; n = 12 in Veh-EqD). *, **, and ***, significant differences (P < 0.05, P < 0.01, and P < 0.001, respectively) between the E2 + ConD and Veh + ConD groups. †, ††, and †††, significant differences (P < 0.05, P < 0.01, and P < 0.001, respectively) between the E2 + EqD and Veh + EqD groups. #, significant differences (P < 0.05) between the Veh + ConD and Veh + EqD groups.