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. 2017 Oct 23;7:13779. doi: 10.1038/s41598-017-13891-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Anti-DBPII reactivity profiles. Reactivity of mouse antisera against the parent antigen Sal1 (a) and four naturally occurring variant DBPII alleles (Fig. S1) by end point titration ELISA. Each curve represents a 4-parameter logistic regression curve for antisera from each mouse (n = 15) against the different alleles (b) Quantitative comparison of reactivity profiles of the different antibodies to the variant DBPII alleles. Each bar represents the serum dilution at EU = 1.0. Error bars represent ± SD.