. 2017 Oct 23;7:13733. doi: 10.1038/s41598-017-13003-0

Table 2.

Fisher’s exact test (P _F) and the uncorrected χ ² test (P _χ ²) of known drug target proteins regarding the inference of the present study.

		Single Gene Perturbations from GEO up					Single Gene Perturbations from GEO down
		F	T	P _F	P _χ ²	RO	F	T	P _F	P _χ ²	RO
heart failure	F	521	517	3.4 × 10⁻⁴	3.9 × 10⁻⁴	3.02	628	416	1.3 × 10⁻³	7.3 × 10⁻⁴	2.61
heart failure	T	13	39	3.4 × 10⁻⁴	3.9 × 10⁻⁴	3.02	19	33	1.3 × 10⁻³	7.3 × 10⁻⁴	2.61
PTSD	F	500	560	3.8 × 10⁻²	3.1 × 10⁻²	2.67	532	529	6.1 × 10⁻³	4.5 × 10⁻³	3.81
PTSD	T	6	18	3.8 × 10⁻²	3.1 × 10⁻²	2.67	5	19	6.1 × 10⁻³	4.5 × 10⁻³	3.81
ALL	F	979	89	2.7 × 10⁻¹	3.0 × 10⁻¹	2.19	1009	57	1.0 × 10⁰	—	—
ALL	T	10	2	2.7 × 10⁻¹	3.0 × 10⁻¹	2.19	12	0	1.0 × 10⁰	—	—
diabetes	F	889	177	1.2 × 10⁻²	7.1 × 10⁻³	3.00	936	130	3.6 × 10⁻⁴	2.0 × 10⁻⁵	5.13
diabetes	T	15	9	1.2 × 10⁻²	7.1 × 10⁻³	3.00	14	10	3.6 × 10⁻⁴	2.0 × 10⁻⁵	5.13
renal carcinoma	F	847	219	2.0 × 10⁻²	1.2 × 10⁻²	2.75	895	169	4.3 × 10⁻²	2.2 × 10⁻²	2.64
renal carcinoma	T	14	10	2.0 × 10⁻²	1.2 × 10⁻²	2.75	16	8	4.3 × 10⁻²	2.2 × 10⁻²	2.64
cirrhosis	F	572	219	1.1 × 10⁻²	8.1 × 10⁻³	2.91	595	169	1.6 × 10⁻³	1.1 × 10⁻³	3.81
cirrhosis	T	8	10	1.1 × 10⁻²	8.1 × 10⁻³	2.91	7	8	1.6 × 10⁻³	1.1 × 10⁻³	3.81

Rows: known drug target proteins (DINIES). Columns: Inferred drug target proteins using ‘Single Gene Perturbations from GEO up’ or ‘Single Gene Perturbations from GEO down’. OR: odds ratio.