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. 2017 Oct 23;7:13818. doi: 10.1038/s41598-017-14274-3

Table 5.

Correlation between TC and categorical variables.

N (%) Tumor circularity P value
Means, standard deviation
Histological type 0.997
  IDC 117 (78) 56.7 ± 1.2
  Non-IDC 33 (22) 57.0 ± 2.2
Pathological grade 0.001*
  low 13 (8.7) 53.9 ± 3.7
  intermediate 63 (42) 52.8 ± 1.5
  high 67 (44.7) 60.9 ± 1.4
  N/A 7 (4.7)
axillary lymph node involvement 0.293
  positive 48 (32) 58.3 ± 2.0
  negative 102 (68) 55.9 ± 1.2
Tumor size (mm) 0.012*
  <15 25 (16.7) 63.0 ± 2.3
  15~24 64 (42.7) 57.4 ± 1.3
  25~35 43 (28.7) 54.5 ± 2.2
  >35 18 (12) 51.6 ± 3.3
ER subset <0.001*
  negative 38 (25.3) 67.0 ± 1.7
  positive 28 (18.7) 57.1 ± 2.2
  strongly positive 84 (56) 51.9 ± 1.2
PR subset <0.001*
  negative 59 (39.3) 64.3 ± 1.5
  positive 41 (27.3) 53.1 ± 1.7
  strongly positive 50 (33.3) 50.7 ± 1.5
Ki67 subset 0.004*
  low 33 (22) 52.8 ± 1.7
  intermediate 66 (44) 54.6 ± 1.5
  high 51 (34) 62.0 ± 1.9
HER-2 group 0.525
  non-expression 57 (38) 58.9 ± 1.8
  low-expression 58 (38.7) 55.2 ± 1.5
  overexpression 35 (23.3) 55.8 ± 2.2
Molecular subtype <0.001*
  luminal A 43 (28.7) 54.7 ± 1.5
  luminal B 69 (46) 52.3 ± 1.5
  HER2-overexpressed 16 (10.7) 61.6 ± 3.2
  TNBC 22 (14.7) 70.8 ± 1.4

*P < 0.05.