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. 2017 Oct 23;7:13836. doi: 10.1038/s41598-017-13064-1

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The HFO area exceeds the resected area in the patient with recurrent seizures (patient 17). (A) Coverage of the implanted electrodes. (B) Reconstruction of surgical resection. Red electrode contacts denote the seizure onset zone (SOZ). The HFO area (contacts filled yellow) is smaller than the SOZ. (C) The resected area (RA) does not comprise all channels of the HFO area. The patient suffers from recurrent seizures. Full resection of the HFO area might have achieved seizure freedom.