Table II.
Various studies depicting effect of age on semen parameters
| Studys | No. of subjects | Significant findings |
|---|---|---|
| Levitas et al 2007 (48) | 6022 | Excellent semen quality at the age of 30-35 years, Sharp reduction in all parameters after 55 years |
| Cardona Maya et al 2009 (49) | 1364 | The decrease in semen volume, motility, sperm concentration, with increasing age |
| Harris et al 2011 (45) | Review | Age related decline in fertility rate and an increase in DNA breakdown in sperms |
| Silva et al 2012 (50) | 975 | Age related changes in nuclear vacuoles and DNA damage |
| Stone et al 2013 (51) | 4822 | Total sperm count and normal morphology declined after 40 years, Sperm motility and semen volume decline after 43 and 45 years of age |
| Purandhar et al 2013 (52) | 90 | Fall in enzymatic antioxidants and neutrophil count with increasing age. The decline in motility, vitality, and morphology with aging |
| Omran et al 2013 (53) | 52 | Fall in sperm density, motility, normal morphology, total antioxidant capacity and DNA integrity with aging |
| Priyadarsini et al 2014 (54) | 733 | Fall in progressive motility, vitality, and morphology with aging. No significant changes were found in semen volume and total count |