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. 2017 Oct 19;7:246. doi: 10.3389/fonc.2017.00246

Table 2.

The prognostic significance of the examined box-count features.a,b

Dbin Dout SFR Λ
Coronal section
0.51 0.74 0.04 0.02
0.42; 0.16–0.68 0.54; 0.29–0.79 0.30; 0.08–0.53 0.21; 0.01–0.40
Sagittal section
0.05 0.92 0.03 0.67
0.30; 0.07–0.49 0.49; 0.24–0.74 0.31; 0.08–0.47 0.45; 0.19–0.71
Transversal section
0.43 1.0 0.20 0.51
0.40; 0.15–0.65 0.50; 0.24–0.76 0.34; 0.11–0.57 0.58; 0.34–0.83
Average
0.08 0.95 0.02 0.32
0.30; 0.06–0.51 0.49; 0.23–0.75 0.20; 0–0.41 0.38; 0.14–0.62

ROC analysis was used for evaluation of predictive significance. Each result indicates a P-value followed by AUC and its 95% confidence interval.

aAUC values and 95% CI are bootstrap corrected.

bObtained with continuous data.

Dbin, fractal dimension obtained on binarized images; Dout, fractal dimension obtained on binarized and outlined images; SFR, ratio of the Dbins obtained on images in which tumor ROI was filled with foreground and background pixels; Λ, lacunarity.

Boldface values indicate significance with p < 0.05.