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. 2017 Oct 23;11:24. doi: 10.1186/s40246-017-0120-8

Fig. 3.

Fig. 3

TagSNPs across the VEGFA gene are associated with disease phenotype (a) and HU treatment efficacy (b). a disease phenotype, rs3024997 (G>A; healthy individuals vs. NTDT patients p = 0.005; β-thalassemia major patients vs. NTDT patients p = 0.003) and rs2146323 (C>A; healthy individuals vs. β-thalassemia major patients p = 0.03; healthy individuals vs. NTDT patients p = 0.0005; β-thalassemia major patients vs. NTDT patients p = 0.009). b HU treatment efficacy, rs2146323 (C>A; HU responders vs. HU non-responders p = 0.0002). HU: hydroxyurea