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. 2017 Oct 23;17:94. doi: 10.1186/s12935-017-0467-x

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — PCDH18 mutations in HCC. a Somatic mutation spectra in 57 HCCs. Nonsynonymous mutations are shown. Functional domains are indicated by colored boxes. b Electropherograms of PCDH18 mutated sequences in HCCs (upper). IHC analysis of HCCs (lower). c qRT-PCR analysis of PCDH18 in HCC2 cells transfected with control or PCDH18-specific siRNAs. d Cell proliferation assay of HCC2 cells transfected with control or PCDH18-specific siRNAs