Table 4.

Clinical variables and the SF-36 for substance use disorder patients with severe mental illness

	Substance use disorder groups with comorbid severe mental illness						Major depressive disorder (n = 36)
	Schizophrenia (n = 37)			Bipolar disorder (n = 34)
SF-36 Dimension	Adjusted R2	IV	ß standardized	Adjusted R2	IV	ß standardized	Adjusted R2	IV	ß standardized
Physical Functioning							0.326	Medical disease comorbidity	−0.588***
Social Functioning	0.408	Positive symptoms (PANSS)	−0.650**
		Medical disease comorbidity	−0.432*
Role-Physical	0.140	Suicide attempts	−0.407*	0.193	Suicide attempts	−0.467**	0.209	Medical disease comorbidity	−0.482**
Role-Emotional				0.476	Medical disease comorbidity	−0.718**
Mental Health	0.347	Medical disease comorbidity	−0.638*	0.427	Severity of substance use disorder (DAST-20)	−0.689**	0.482	Depressive symptoms (HDRS)	−0.719**
Vitality	0.448	Drug relapses	−0.669*
Bodily Pain	0.247	PANSS composite score	−0.532*				0.177	Depressive symptoms (HDRS)	−0.469*
General Health							0.222	Medical disease comorbidity	−0.494**

SF-36: Short Form Health Survey

In all cases Tolerance values were higher than 0.954 and Variance Inflation Factor were higher than 1

*p < 0.05, **p < 0.01; ***p < 0.001