Table 1.
Clinical factor | No. | HOXD10 methylation status | *P value | |
---|---|---|---|---|
Unmethylated n = 27 (23.1%) | Methylated n = 90 (76.9%) | |||
Age (year) | 0.799 | |||
< 60 | 80 | 19 | 61 | |
≥ 60 | 37 | 8 | 29 | |
Gender | 0.248 | |||
Male | 101 | 21 | 80 | |
Female | 16 | 6 | 10 | |
HBV infection | 0.762 | |||
Yes | 85 | 19 | 66 | |
No | 32 | 8 | 24 | |
Liver cirrhosis | 0.093 | |||
Yes | 88 | 17 | 71 | |
No | 29 | 10 | 19 | |
Tumor size (cm) | 0.231 | |||
≤ 5 | 37 | 6 | 31 | |
> 5 | 80 | 21 | 59 | |
Number of lesions | 0.681 | |||
1 | 92 | 22 | 70 | |
≥ 1 | 25 | 5 | 20 | |
Differentiation | 0.044* | |||
Well | 8 | 4 | 4 | |
Moderate | 74 | 19 | 55 | |
Poor | 35 | 4 | 31 | |
TNM stage | 0.377 | |||
Stage I + stage II | 52 | 14 | 38 | |
Stage III + stage IV | 65 | 13 | 52 | |
Lymph node metastasis | 0.867 | |||
Negative | 112 | 26 | 86 | |
Positive | 5 | 1 | 4 | |
Vessel cancerous embolus | 0.049* | |||
Negative | 87 | 24 | 63 | |
Positive | 30 | 3 | 27 |
*P values are obtained from chi-square test, significant difference, *P < 0.05