Table 4.
Effect of radiation field and dose on cognitive functions
| Variable | Radiation field |
Radiation dose, Gy |
||||
|---|---|---|---|---|---|---|
| T2-T1 difference (mean±SD) |
p-value | T2-T1 difference (mean±SD) |
p-value | |||
| CSI | WVI | ≤ 39.6 | > 39.6 | |||
| FIQ | –0.80±17.79 (n=10) | 5.30±6.04 (n=10) | 0.327 | 4.41±9.14 (n=12) | –1.00±18.14 (n=8) | 0.387 |
| VIQ | –3.22±15.06 (n=9) | 4.00±8.38 (n=10) | 0.207 | 1.58±9.66 (n=12) | –1.14±16.50 (n=7) | 0.653 |
| PIQ | 0.22±23.60 (n=9) | 6.30±8.87 (n=10) | 0.458 | 7.33±14.37 (n=12) | –3.29±20.69 (n=7) | 0.203 |
| VC | 1.14±8.63 (n=7) | 2.63±9.23 (n=8) | 0.754 | 1.10±8.95 (n=10) | 3.60±8.79 (n=5) | 0.617 |
| PO | –4.00±14.85 (n=6) | 8.25±6.34 (n=8) | 0.078 | 4.80±11.30 (n=10) | –2.00±14.68 (n=5) | 0.336 |
| FD | –7.83±9.02 (n=6) | 5.00±14.44 (n=8) | 0.081 | 2.00±14.60 (n=10) | –6.75±9.91 (n=4) | 0.297 |
| PS | –12.67±24.30 (n=6) | 1.38±14.27 (n=8) | 0.199 | –3.78±20.43 (n=9) | –6.20±20.61 (n=5) | 0.836 |
| MQ | 1.80±16.31 (n=10) | 4.44±10.50 (n=9) | 0.684 | 5.09±10.11 (n=11) | 0.25±17.65 (n=8) | 0.458 |
| EIQ | 2.60±19.97 (n=5) | 4.38±14.88 (n=8) | 0.857 | 0.50±16.30 (n=10) | 14.33±12.66 (n=3) | 0.208 |
SD, standard deviation; CSI, craniospinal irradiation; WVI, whole ventricle irradiation; FIQ, full-scale intelligence quotient (IQ); VIQ, verbal IQ; PIQ, performance IQ; VC, verbal comprehension; PO, perceptional organization; FD, freedom of distractibility; PS, processing speed; MQ, memory quotient; EIQ, executive IQ.