Table 3.
Analyses of the treatment modalities according to the education level and clinicopathologic characteristics in the subgroup aged > 50 years
Characteristic (age > 50 yr) | Operation |
Radiation therapy |
Chemotherapy |
Endocrine therapy |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lumpectomymastectomy | Chi-square p-value | No | Yes | Chi-square p-value | No | Yes | Chi-square p-value | No | Yes | Chi-square p-value | ||
All | ||||||||||||
Low education level | 6,814 (47.8) | 7,437 (52.2) | < 0.001 | 5,317 (43.5) | 6,915 (56.5) | < 0.001 | 4,018 (31.7) | 8,661 (68.3) | 0.029 | 3,955 (44.9) | 4,859 (55.1) | < 0.001 |
High education level | 7,055 (59.2) | 4,863 (40.8) | 3,571 (33.8) | 6,994 (66.2) | 3,610 (33.0) | 7,321 (67.0) | 3,354 (40.1) | 5,017 (59.9) | ||||
Tumor size ≤ 2 cm | ||||||||||||
Low education level | 4,659 (61.2) | 2,957 (38.8) | < 0.001 | 2,503 (38.2) | 4,050 (61.8) | < 0.001 | 2,867 (42.9) | 3,811 (57.1) | 0.083 | 1,887 (38.5) | 3,014 (61.5) | < 0.001 |
High education level | 5,077 (69.5) | 2,230 (30.5) | 1,932 (29.7) | 4,574 (70.3) | 2,954 (44.4) | 3,696 (55.6) | 1,833 (34.7) | 3,448 (65.3) | ||||
Tumor size > 2 cm | ||||||||||||
Low education level | 2,027 (31.7) | 4,376 (68.3) | < 0.001 | 2,741 (50.0) | 2,742 (50.0) | < 0.001 | 1,075 (18.6) | 4,719 (81.4) | < 0.001 | 1,943 (52.0) | 1,791 (48.0) | < 0.001 |
High education level | 1,804 (41.6) | 2,532 (58.4) | 1,545 (40.5) | 2,274 (59.5) | 523 (13.0) | 3,509 (87.0) | 1,371 (47.6) | 1,510 (52.4) | ||||
Node negative | ||||||||||||
Low education level | 4,881 (55.1) | 3,971 (44.9) | < 0.001 | 3,467 (45.6) | 4,129 (54.4) | < 0.001 | 3,339 (43.0) | 4,426 (57.0) | 0.042 | 2,485 (45.8) | 2,945 (54.2) | < 0.001 |
High education level | 5,267 (66.1) | 2,698 (33.9) | 2,445 (34.5) | 4,649 (65.5) | 3,235 (44.6) | 4,011 (55.4) | 2,282 (40.6) | 3,334 (59.4) | ||||
Node positive | ||||||||||||
Low education level | 1,857 (35.3) | 3,403 (64.7) | < 0.001 | 1,792 (39.5) | 2,746 (60.5) | < 0.001 | 614 (12.8) | 4,197 (87.2) | < 0.001 | 1,435 (43.2) | 1,885 (56.8) | < 0.001 |
High education level | 1,714 (44.8) | 2,114 (55.2) | 1,089 (32.1) | 2,301 (67.9) | 323 (9.0) | 3,275 (91.0) | 1,038 (38.6) | 1,649 (61.4) | ||||
Stage I | ||||||||||||
Low education level | 3,683 (63.7) | 2,103 (36.3) | < 0.001 | 1,946 (39.0) | 3,041 (61.0) | < 0.001 | 2,630 (52.2) | 2,406 (47.8) | 0.066 | 1,466 (39.3) | 2,262 (60.7) | < 0.001 |
High education level | 4,153 (72.0) | 1,613 (28.0) | 1,518 (29.4) | 3,637 (70.6) | 2,818 (54.0) | 2,397 (46.0) | 1,450 (34.5) | 2,754 (65.5) | ||||
Stage II, III | ||||||||||||
Low education level | 2,940 (36.2) | 5,172 (63.8) | < 0.001 | 3,267 (46.8) | 3,711 (53.2) | < 0.001 | 1,273 (17.3) | 6,087 (82.7) | < 0.001 | 2,368 (48.7) | 2,490 (51.3) | < 0.001 |
High education level | 2,685 (46.3) | 3,116 (53.7) | 1,944 (37.8) | 3,196 (62.2) | 644 (11.9) | 4,770 (88.1) | 1,753 (44.5) | 2,183 (55.5) | ||||
Hormonal receptor negative | ||||||||||||
Low education level | 1,817 (41.1) | 2,607 (58.9) | < 0.001 | 1,832 (45.9) | 2,161 (54.1) | < 0.001 | 660 (15.8) | 3,526 (84.2) | 0.828 | NA | NA | |
High education level | 1,787 (52.1) | 1,644 (47.9) | 1,172 (37.3) | 1,973 (62.7) | 510 (15.6) | 2,763 (84.4) | NA | NA | ||||
Hormonal receptor positive | ||||||||||||
Low education level | 4,413 (51.7) | 4,119 (48.3) | < 0.001 | 3,172 (41.2) | 4,520 (58.8) | < 0.001 | 3,139 (39.7) | 4,760 (60.3) | 0.208 | 493 (10.2) | 4,334 (89.8) | 0.015 |
High education level | 4,773 (62.5) | 2,864 (37.5) | 2,207 (31.5) | 4,801 (68.5) | 2,943 (40.7) | 4,280 (59.3) | 445 (8.8) | 4,620 (91.2) | ||||
Lumpectomy | ||||||||||||
Low education level | NA | NA | 529 (9.0) | 5,353 (91.0) | < 0.001 | 2,117 (35.7) | 3,815 (64.3) | 0.007 | 1,680 (30.2) | 3,879 (69.8) | 0.418 | |
High education level | NA | NA | 433 (6.9) | 5,803 (93.1) | 2,415 (38.0) | 3,937 (62.0) | 1,776 (29.5) | 4,238 (70.5) | ||||
Mastectomy | ||||||||||||
Low education level | NA | NA | 4,737 (76.4) | 1,462 (23.6) | 0.001 | 1,829 (27.8) | 4,756 (72.2) | 0.025 | 2,220 (70.8) | 914 (29.2) | 0.032 | |
High education level | NA | NA | 3,092 (73.6) | 1,109 (26.4) | 1,147 (25.8) | 3,291 (74.2) | 1,532 (68.1) | 717 (31.9) |
NA, not applicable.