Fig. 6.

Ursolic acid and scopoletin suppresses concanavalin A- and LPS-induced proliferation of primary mouse splenocytes. (A), (B). Primary splenocytes isolated from Balb/c mice were stimulated with concanavalin A (ConA; 5 μg/mL) or lipopolysaccharide (LPS; 10 μg/mL) in the presence or absence of ursolic acid, hyperoside, scopoletin, and scopolin for 24 hr. Cellular proliferation was measured by methylthiazol tetrazolium (MTT) assay. Data are mean ± SEM (n = 3). *Significantly different from ConA or LPS alone, p < 0.05. Veh, vehicle.