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. Author manuscript; available in PMC: 2017 Oct 24.
Published in final edited form as: JACC Heart Fail. 2016 Sep 7;4(10):761–768. doi: 10.1016/j.jchf.2016.05.010

Table 1.

Baseline characteristics of study population

BMI <18.5 18.5 ≤ BMI < 25 25 ≤ BMI < 30 30 ≤ BMI < 35 BMI ≥ 35 p-value
N= 84 N= 983 N= 1,368 N= 1,028 N= 393
Age 43 (15.5–57) 56 (45–63) 57 (48–63) 55 (45–61) 49 (40–57) <0.0001
Male (%) 44 (52.4) 716 (72.8) 1,086 (79.4) 827 (80.5) 281 (71.5) <0.0001
ICM (%) 17 (20.2) 390 (39.7) 691 (43.2) 425 (41.3) 138 (35.1) <0.0001
Race (%) <0.0001
   White 43 (51.2) 618 (62.9) 957 (70.0) 674 (65.6) 222 (56.5)
   Black 28 (33.3) 240 (24.4) 289 (21.1) 260 (25.3) 144 (36.6)
Device Type (%) <0.0001
   Heartmate II 49 (58.3) 797 (81.1) 1,179 (86.2) 887 (86.3) 333 (84.7)
   Heartware HVAD 35 (41.7) 186 (18.9) 189 (13.8) 141 (13.7) 60 (15.3)
GFR (MDRD) 101.1 (66.8–135.0) 75.9 (52.8–89.0) 64.8 (50.4–84.1) 62.8 (47.8–78.7) 61.7 (46.9–78.2) <0.0001
CrCl (Cockcroft-Gault) 73.2 (54.3–98.8) 73.2 (54.3–93.9) 73.5 (56.7–95.0) 66.8 (52.2–87.4) 67.6 (51.8–87.4) <0.0001
Adj Body Wt CrCl 73.2 (54.3–98.8) 73.2 (54.3–93.9) 76.7 (59.5–99.3) 76.2 (59.4–97.9) 82.1 (62.5–107.4) <0.0001
Creatinine (mg/dL) 0.9 (0.7–1.1) 1.1 (0.9–1.4) 1.2 (0.9–1.5) 1.2 (1.0–1.5) 1.3 (1.0–1.6) <0.0001
Dialysis (%) 2 (2.4) 33 (3.4) 32 (2.3) 38 (3.7) 12 (3.1) 0.37
Hemodynamics
   mPAP (mmHg) 30 (25–37) 30 (22–37) 30 (22–38) 31 (23–39) 33 (25–42) <0.0001
   PCWP (mmHg) 23 (15–28) 20 (12–27) 20 (13–27) 20 (14–27) 22 (16–29) 0.0008
   PVR (WU) 2.55 (1.79–4.23) 2.45 (1.59–3.61) 2.27 (1.45–3.33) 2.24 (1.43–3.24) 2.11 (1.37–3.01) <0.0001
   CO (L/min) 2.9 (2.4–3.8) 3.8 (3.1–4.7) 4.3 (3.5–4.2) 4.6 (3.7–5.5) 4.9 (4.0–5.8) <0.0001
   CI (L/min/m2) 1.87 (1.61–2.42) 2.12 (1.73–2.56) 2.13 (1.74–2.55) 2.08 (1.70–2.50) 2.09 (1.74–2.45) 0.12
Diabetes (%) 6 (7.1) 179 (18.3) 438 (32.0) 435 (42.5) 173 (44.0) <0.0001
ICD (%) 51 (60.7) 726 (74.0) 1,092 (79.9) 833 (81.3) 326 (83.0) <0.0001
Prior Smoker (%) 26 (31.0) 458 (46.8) 749 (54.9) 567 (55.5) 193 (49.4) <0.0001
Prior Stroke (%) 4 (4.8) 54 (5.5) 84 (6.2) 60 (5.9) 15 (3.8) 0.28
Transplanted (%) 59 (70.2) 742 (75.5) 988 (72.2) 706 (68.7) 228 (58.0) <0.0001

Data presented as Count (%) or Median (interquartile range). BMI=Body Mass Index; CrCl=Creatinine Clearance in mL/min; CI=Cardiac Index; GFR=Glomerular Filtration Rate in mL/min/1.73 m2; ICD=Implantable Cardioverter Defibrillator; ICM=Ischemic Cardiomyopathy; mPAP=Mean Pulmonary Artery Pressure; PCWP=Pulmonary Capillary Wedge Pressure; PVR=Pulmonary Vascular Resistance