Table 4.
Summary of numerical and structural aberrations observed in cancer stem cells and nonstem tumor cells
| Model ID | Numerical Aberrations |
Structural Aberrations |
||||||
|---|---|---|---|---|---|---|---|---|
| Total in CSC | Shared in NSTCs | Lost in NSTCs | New in NSTCs | Total in CSC | Shared in NSTCs | Lost in NSTCs | New in NSTCs | |
| ICb-984MB | 14 | 14 | 0 | 0 | 8 | 8 | 0 | 2 |
| ICb-1299MB | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 0 |
| ICb-1572MB | 1 | 1 | 0 | 0 | 3 | 3 | 0 | 0 |
| ICb-1338MB | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
| ICb-1595MB | 9 | 3 | 6 | 4 | 0 | 0 | 0 | 0 |
| ICb-1078MB | 11 | 6 | 5 | 8 | 4 | 3 | 1 | 0 |
| ICb-1494MB | 14 | 11 | 3 | 4 | 1 | 1 | 0 | 0 |
| ICb-61109MB | 2 | 2 | 0 | 0 | 5 | 5 | 0 | 0 |
| ICb-J1017MB | 5 | 5 | 0 | 0 | 2 | 2 | 0 | 3 |
| MB Total | 59 | 45 | 14 | 17 | 24 | 23 | 1 | 5 |
| (%)a | 76.3% | 23.7% | (28.8%) | 95.9% | 4.1% | (20.8%) | ||
| IC-1227AA | 8 | 8 | 0 | 0 | 15 | 15 | 0 | 1 |
| IC-1502GBM | 5 | 3 | 2 | 2 | 14 | 5 | 9 | 8 |
| IC-3704GBM | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| IC-3752GBM | 4 | 3 | 1 | 0 | 7 | 7 | 0 | 0 |
| IC-1128GBM | 9 | 8 | 1 | 0 | 11 | 9 | 2 | 1 |
| IC-2305GBM | 21 | 21 | 0 | 0 | 14 | 11 | 3 | 1 |
| IC-1406GBM | 4 | 2 | 2 | 7 | 0 | 0 | 0 | 7 |
| HGGb Total | 52 | 46 | 6 | 9 | 61 | 47 | 14 | 18 |
| (%) | 88.5% | 11.5% | (17.3%) | 77.1% | 22.9% | (29.5%) | ||
Abbreviations: AA, astrocytoma; CSCs, cancer stem cells; GBM, glioblastoma multiforme; NSTCs, nonstem tumor cells.
aPercentage of the total numerical or structural changes in CSCs.
bHGG includes both AA and GBM.