Figure 3.

Comparison of % tumor growth among 3 groups of mice (a) and expanded view of the 2 treated groups (b). Group 1 mice were breathing air and not treated [triangles; n = 4]. Group 2 mice were breathing carbogen and their tumors were radiated [diamonds; n = 8]. Group 3 mice were breathing carbogen, were dosed with 0.6 mL/kg NVX-108 and their tumors were radiated [circles; n = 8]. The slopes of the trend lines are significantly different among all 3 groups (p < 0.05). Most notably, the rate of tumor growth (slope) in radiated mice treated with NVX-108 was 25 times slower compared to untreated mice (p < 0.0001) and 2 times slower compared to radiated mice (p = 0.01).