Table 4.

Behavior Rating Inventory of Executive Function (BRIEF) and Vineland Adaptive Behavior Scales

	KCNJ11-related NDM with global developmental delay	KCNJ11-related NDM without delay	Sibling controls	ANOVA P value	KCNJ11-related NDM without delay vs Controls P value
BRIEF (n) (T scores)	5	10	14
Inhibit	71.6±10.6	59.2±13.7	50.0±11.9	<0.05	NS (0.09)
Shift	61.4±9.4	54.3±10.4	46.9±8.8	<0.05	NS
Emotional Control	61.8±13.2	50.4±12.2	49.6±10.3	NS	NS
Working Memory	72.3±7.1	61.3±13.1	48.2±11.7	<0.01	<0.05
Plan/Organize	64.4±10.7	59.7±14.7	48.1±12.7	<0.05	<0.05
Megacognition Index	71.5±6.8	59.9±11.4	47.5±12.8	<0.01	<0.05
Global Executive Composite	72.8±6.8	59.3±12.3	47.6±12.1	<0.005	<0.05
Vineland (n) (V-scale/ Standard Scores)	7	11	7
Receptive	12.0±6.2	14.5±4.7	16.0±2.1	NS	NS
Expressive	9.4±4.2	12.5±3.9	17.3±3.3	<0.01	<0.05
Written	11.3±8.2	12.1±3.1	15.7±3.7	<0.05	NS (0.07)
Communication	75.3±33.9	89.8±20.2	109.4±19.2	<0.05	<0.05
Personal	9.1±4.4	16.0±4.6	16.4±3.5	<0.05	NS
Domestic	11.0±3.2	12.7±3.5	15.9±1.9	<0.05	<0.05
Community	8.3±4.2	13.7±3.2	17.9±1.6	<0.001	<0.05
Daily Living Skills	69.7±16.8	94.7±15.7	110.0±14.1	<0.005	NS
Interpersonal	10.3±2.4	12.0±4.0	16.9±1.9	<0.01	<0.05
Play and Leisure	8.6±2.9	13.0±3.7	15.1±2.4	<0.01	NS
Coping	10.7±3.2	16.7±3.0	16.7±1.8	<0.05	NS
Socialization	66.0±7.8	95.2±16.0	107.7±10.9	<0.005	NS
Adaptive Behaviour Composite	69.7±19.8	94.8±18.0	107.7±16.5	<0.05	NS

NS, Not statistically significant