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. Author manuscript; available in PMC: 2017 Oct 24.
Published in final edited form as: Arch Toxicol. 2016 Nov 8;91(5):2245–2261. doi: 10.1007/s00204-016-1885-6

Figure 8. Panx1 channel inhibition promotes liver regeneration following APAP overdosing.

Figure 8

Mice (n = 10 per group) were injected 300 mg/kg APAP followed by administration of 10 mg/kg 10Panx1 or saline (SAL) 1.5 hours later. Sampling was performed 24 hours after APAP overdosing. Hepatic protein levels of PCNA were assessed by immunoblot analysis and expressed as relative alteration compared to APAP-treated animals followed by SAL administration. Data are expressed as means ± SEM, with *p < 0.05 compared to APAP followed by vehicle administration.