Table 4.

Cross-tabulation of baseline characteristics and LVSD/asymptomatic LVEF decline

	Total number of patients	No cardiac toxicity	LVSD or Asymptomatic LVEF Decline	RR (95% CI)	p
		n (%)	n (%)
Age at study entry (yrs)
<50	132	126 (95)	6 (5)	-	0.58
≥50	274	265 (97)	9 (3)	0.72 (0.26-1.99)
Baseline LVEF (%)
≤55	40	36 (90)	4 (10)	-	0.05
>55	366	355 (97)	11 (3)	0.30 (0.10-0.90)
History of Hypertension
Yes	118	113 (96)	5 (4)	-	0.77
No	288	278 (97)	10 (3)	0.82 (0.29-2.35)
History of Diabetes
Yes	30	27 (90)	3 (10)	-	0.09
No	376	364 (97)	12 (3)	0.32 (0.10-1.07)

LVSD: Left ventricular systolic dysfunction

LVEF: Left ventricular ejection fraction